Portofino, Italy

This postcard-perfect destination, with its pastel-colored houses encircling the port, may be one of the most photographed in all of Italy. If you can take your eyes off the scenery, there is much to explore in and around Portofino. The 12th-century Church of St. George and the medieval Castello Brown both afford spectacular views of the harbor. A long, scenic hike or a short boat ride takes you to the restored 11th-century abbey in San Fruttuoso. Northwest of Portofino lies Genoa, filled with museums, palaces and the grand Cathedral of San Lorenzo. Portofino is also only an hour away from famous Cinque Terre, a UNESCO World Heritage site of five colorful villages built into the cliffs overlooking the sea.